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Complete guide how to get a job in new Zealand from India

How to get a job in new Zealand from India As a  Indian guy I am also dreaming to work in new Zealand, because of its culture beauty and easy living. I am planning to work in NZ since 10 years but due to my blood cancer I am not able to apply for job there and I am not getting works visa for fitness job. But here I want to share my experience and tips to to direct job in NZ from India. 
Although getting work visa for new Zealand is hard these days because of changing in visa rules and regulation. If you apply for visa on your own I am sure you will not get working visa, so what are other option to apply for job there. There is one best option to seek help of NZ immigration agents who can help you with all paper work and make your best profile and resume, work experience and describe you all the things about new Zealand.

New Zealand work visa requirements for Indian citizens
Second option apply for get tourist visa for new Zealand, this option cost you money  but at least you get all t…

What is acute promyelocytic leukemia and treatment for (APL)

Acute promyelocytic leukemia and treatment for (APL)

Acute Promyelocytic Leukemia is an uncommon subtype of Acute Myeloid Leukemia (AML m3). Often it is diagnosed in young and middle aged adults but it can also occur in children and older adults. APL is characterized by the structure of certain cells called blast cells, the chromosomal translocation t(15;17), and a defect with the body's blood clotting mechanism.

Acute promyelocytic leukemia,acute promyelocytic leukemia treatment

There are different types of leukemia, and acute promyelocytic leukemia is one of the subtypes of this blood disorder. Medical specialists have discovered unique characteristics and clinical representations of this type of acute leukemia. The disease was first termed as fatal, when it was discovered. However, doctors have introduced many forms of treatment. At present, the disease is curable, and those who suffer from acute promyelocytic leukemia have experienced positive response to medication and therapy.

A few percentage of people may suffer from acute promyelocytic leukemia, a unique type of leukemia associated with certain biologic and clinical characteristics. Those who have this disorder have a decrease in the plasminogen levels, as well as the alpha 2-plasmin inhibitor. In all cases of patients with this leukemia, there is an observed increase in the production of fibrinolysis and plasmin.

Patients that suffer from acute leukemia may have cogulopathy, and this is a medical emergency. Those who are untreated for leukemia may suffer from cerebral hemorrhages that can be fatal. Typically, medication for coagulopathy takes about 8 days to become effective.

Acute promyelocytic leukemia symptoms

Patients with acute promyelocytic leukemia are observed to show -

  • Bleeding in the gums.
  • Petechiae.
  • Headache.
  • Low platelets counts.
  • Bledding from nose.
  • Swelling in the gums.
  • Easy to bleed while brushing teeth.

When a patient also suffers from severe anemia, there is a flow murmur that may be observed from physical examinations. An involvement of the central nervous system can result to severe headaches among patients. Other people who suffer from the disease may experience additional symptoms depending on the affected part of the body.

Acute promyelocytic leukemia diagnosis

Those who experience symptoms should visit their doctor, so that further tests may be made. The initial test that is done for the diagnosis of acute promyelocytic leukemia is a complete blood count. The CBC test will reveal the actual number of essential blood groups in the body. The doctor will request for a peripheral blood smear, differential count, and metabolic profile for liver and renal function tests. Additional tests include fibrinogen measurements, prothrombin time, and electrolyte levels.

Some patients may have an existing high amount of white blood cell, and they are considered as high risk patients. Those who have such characteristics should undergo lumbar puncture in order for doctors to diagnose the presence of acute promyelocytic leukemia. However, a patient that suffers from coagulopathy needs to obtain medication from this symptom. The doctor may advise for the delay of lumbar puncture, so that coagulopathy will be treated.

Acute promyelocytic leukemia treatment

The best treatment for patients depends on the particular case or stage of the disease. Medical specialists and trained doctors can provide the ideal supportive and pharmacologic treatment to patients. In some cases, platelet transfusion may be required for patients with severe decrease in platelet count.

Treatment options for this type of acute leukemia include different phases such as induction, maintenance, and consolidation. For elderly patients, doctors may recommend induction therapy as the ideal treatment option.

However, some patients respond perfectly in maintenance therapy. In fact, this method is effective for patients that suffer from relapse.
Patients with severe cases of the disease can benefit from consolidation and induction therapy.

Chemotherapy and drugs such as ATRA,Anthracycline and Arsenic trioxide and antibiotics to treat infection is proven to be an effective treatment for patients with acute promyelocytic leukemia.


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